See Tweets about #canfour on Twitter. #Cantargia Reports Interim #Data from Phase 2A #CANFOUR Trial of CAN04 in #Pancreatic and #LungCancers

In the CANFOUR part examining PDAC, 9 patients in the first cohort of 31 are currently on treatment with CAN04 in combination with gemcitabine and nab-paclitaxel. An interim analysis of 20 patients in October 2020 showed a 40% response rate (including 2 patients that had not been treated long enough for a second confirmatory CT-scan), which is higher than 23% reported as historical control 1 .

I enlighet med protokollet behandlas patienterna i grupper om tre. The results from the CANFOUR study for Cantargia's candidate CAN04 are imminent, due in Q4 2019 and early 2020. The outcome will, in our view, represent a major valuation trigger for the share and potentially also lead to a partnership deal. I den del av CANFOUR som innefattar PDAC behandlas fortfarande 9 av 31 patienter i den primära kohorten med CAN04 i kombination med gemcitabin och nab-paclitaxel.

23 aug 2019 Målmolekylen för CAN04, IL1RAP, har påvisats på cancercellerna hos Den pågående kliniska studien CANFOUR undersöker CAN04 med 20 Oct 2018 CANFOUR clinical trial presented in a poster presentation during the Germany, shows that 6 mg/kg of nidanilimab (CAN04; Cantargia AB) 6 Nov 2019 An open label, dose escalation followed by dose expansion, safety and tolerability trial of CAN04, a fully humanized monoclonal antibody 7 Dec 2017 Cantargia's main candidate is the immunotherapy CAN04, an cancer and non- small cell lung cancer (NSCLC) in the phase I/IIa trial Canfour. 11 Dec 2019 Cantargia's lead product, CAN04 is being tested in the CANFOUR Phase 1/2a clinical trial in people with pancreatic cancer and non-small cell Öppen fas I/IIa studie för att undersöka säkerhet och tecken på effekt vid behandling med CAN04. Fas I – doseskalering med säkerhetsutvärdering. Initierades efter Can04 är en antikropp som har IL-1RAP som mål.

Here, CAN04 is examined as monotherapy or in chemotherapy combinations in patients with non-small cell lung cancer (NSCLC) or pancreatic cancer (PDAC). All 20 patients planned for one of these arms, monotherapy, CanFour är en Fas-1 studie med en ny läkemedel Can04.

Vi tror att den trend som CAN04 visade upp i de preliminära data som Även om CANFOUR-studien, som pågått sedan 2017, har dragits med

The study is focused on Cantargia is a clinical-stage biotechnology company based in Sweden, established in 2009 and listed on the Nasdaq Stockholm main market. It is developing two assets against IL1RAP, CAN04 and CAN10. CAN04 is being studied in a Phase IIa clinical trial, CANFOUR, in solid tumours focusing on NSCLC and pancreatic cancer. CAN04 is a humanized and antibody-dependent cellular cytotoxicity (ADCC)-enhanced IgG1 antibody targeting IL1RAP with two modes of action: blocking IL-1 alpha and beta signaling and triggering ADCC.

Cantargia AB today announced that the first patient with pancreatic cancer has started treatment in the phase IIa extension part of the CANFOUR trial, investigating combination of CAN04 and | April 6, 2021

The results from the CANFOUR study for Cantargia's candidate CAN04 are imminent, due in Q4 2019 and early 2020. The outcome will, in our view, represent a major valuation trigger for the share and potentially also lead to a partnership deal. I den del av CANFOUR som innefattar PDAC behandlas fortfarande 9 av 31 patienter i den primära kohorten med CAN04 i kombination med gemcitabin och nab-paclitaxel. En interimsanalys av 20 patienter i oktober 2020 visade på s.k.

A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors (CANFOUR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. In the CANFOUR part examining PDAC, 9 patients in the first cohort of 31 are currently on treatment with CAN04 in combination with gemcitabine and nab-paclitaxel. An interim analysis of 20 patients in October 2020 showed a 40% response rate (including 2 patients that had not been treated long enough for a second confirmatory CT-scan), which is higher than 23% reported as historical control 1 . Cantargia´s antibody CAN04 (nidanilimab) is investigated in an open label three-armed phase IIa clinical trial, CANFOUR. Here, CAN04 is examined as monotherapy or in chemotherapy combinations in patients with non-small cell lung cancer (NSCLC) or pancreatic cancer (PDAC). All 20 patients planned for one of these arms, monotherapy, CanFour är en Fas-1 studie med en ny läkemedel Can04.
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It is developing two assets against IL1RAP, CAN04 and CAN10. CAN04 is being studied in a Phase IIa clinical trial, CANFOUR, in solid tumours focusing on NSCLC and pancreatic cancer.

Can04 är en antikropp som har IL-1RAP som mål.
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Cantargia AB: Cantargia reports first patient treated with CAN04 in a US phase I study investigating combination with pembrolizumab. Publicerad: 2020-10-02 (Cision) Cantargia AB: Cantargia rapporterar att första patienten behandlats med CAN04 i en fas I studie i USA som studerar kombination med pembrolizumab

Huvudprojektet, antikroppen CAN04, studeras i den kliniska fas I/IIa-studien CANFOUR med primärt fokus mot icke-småcellig lungcancer och bukspottskörtelcancer. Studien genomförs som både monoterapi och kombinationsterapi. The company announces the status of the ongoing phase I/IIa clinical trial CANFOUR investigating the lead compound CAN04 (nidanilimab) and further information on the phase IIa part of the trial. So far, 15 patients have received therapy in the phase I safety part of the study, and generally the immuno-oncology antibody CAN04, targeting IL1RAP, has been well tolerated.

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Cantargia completes recruitment and reports positive interim update in CAN04 pancreatic cancer combination therapy Thu, Oct 08, 2020 16:45 CET. Cantargia AB today announced that all 31 pancreatic cancer (PDAC) patients planned in the CANFOUR trial investigating combination of CAN04 and chemotherapy have started treatment.

CAN04 binder interleukin 1 receptor accessory protein (IL1RAP), studeras i den kliniska fas I/IIa-studien CANFOUR med primärt fokus mot Positiva interimsresultat presenterades från fas 2a-studien CANFOUR för kombinationsbehandling med CAN04 och cellgifter av patienter med Cantargia's Phase IIa CANFOUR trial investigates CAN04 in a combination with a different chemotherapy (platinum-based as opposed to docetaxel in the Analysguiden: Andra halvlek i CANFOUR genomför riktad nyemission om cirka 106 miljoner kronor för utökad klinisk satsning på CAN04. Alla 31 planerade patienter med bukspottkörtelcancer (PDAC) har påbörjat behandling i Canfour-studien som undersöker kombination av CAN04 med cellgifter. CAN04 - man kan sätta sig och räkna och komma fram till allt mellan 5 och 10 Cantargia: Ytterligare Alla 31 planerade patienter har påbörjat behandling i CANFOUR-studien som undersöker CAN04 kombinerat med cellgifter. Rapporterade (R) Cantargia rapporterar att första patienten behandlats med CAN04 i en fas I antikroppen CAN04, studeras i den kliniska fas I/IIa-studien CANFOUR med procent efter att ha fått positiva interimsdata från den pågående fas IIa-studien Canfour.